Platelet-Rich Plasma on Ankle Sprains – Efficacy on Pain Reduction and Shorter Return to Play: A Systematic Review of Available Randomized Control Trials

Background: The role of platelet-rich plasma (PRP) has been widely studied, but only recently did trials emerge that probed into its potential in ankle sprains. With the limited available literature, most results showed it might have a faster healing and pain reduction. Objectives: purpose this review is to summarize studies on sprains order identify if there good initial evidence return play (RTP) among active individuals as well It also were consistent studies. Methodology: A systematic search literature online databases was done compare about outcome measures score RTP. Included are those with population 18 years above treated PRP or without post-procedural immobilization. Outcome scorings assessed parameter included. Results: Three randomized controlled two prospective identified. Results an average 8 weeks RTP (p-value - 0.006) decreased functional therapy. Limitation: Only one trial (RCT) compared placebo small all made available. More comparable RCTs needed strengthen Conclusion: use may shorter time Key words: Ankle Sprains, Lateral Platelet-rich Plasma